MOTS-C
The exercise mimetic peptide
MOTS-C is a mitochondrial-derived peptide that acts as an exercise mimetic. It activates AMPK — the same pathway triggered by exercise — making it a powerful tool in metabolic regulation, fat oxidation, and cellular energy research. It is one of the most exciting peptides in longevity science.
Research Benefits
How It Works
MOTS-C activates the AMPK signalling pathway, which is the body's master metabolic switch. This promotes glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. It essentially mimics the metabolic benefits of exercise at the cellular level.
Quick Reference — MOTS-C
10 mg / 20 mg vials
10 mg: 1 mL | 20 mg: 2 mL bac water
10 mg/mL
5–10 mg (0.5–1.0 mL)
3–5× per week. Often cycled: 4 weeks on / 2 weeks off
SC or IM injection
Refrigerate; use within 30 days
Requires bacteriostatic water for reconstitution — available in our store. Best dosed pre-workout for exercise performance benefits. Significant insulin sensitising effect — useful for metabolic syndrome. Can be combined with Retatrutide for metabolic stack.
For research purposes only. Not for human consumption. Always consult qualified professionals.
Pairs well with
MOTS-C + NAD+ is a powerful cellular energy stack — MOTS-C activates AMPK while NAD+ fuels mitochondrial function. Adding Retatrutide amplifies fat loss through appetite control, and Tesamorelin specifically targets visceral adipose tissue.
Questions about MOTS-C?
Our team responds within 24 hours. Reach out for bulk pricing, stacking advice, or technical questions.