Retatrutide
Triple-action metabolic powerhouse
Retatrutide is a next-generation triple agonist peptide targeting GLP-1, GIP, and glucagon receptors simultaneously. In clinical research, it has demonstrated the most significant weight reduction results of any peptide studied to date, with effects on appetite regulation, metabolic rate, and fat oxidation.
Research Benefits
How It Works
Retatrutide activates GLP-1 receptors to reduce appetite and slow gastric emptying, GIP receptors to improve insulin response and fat metabolism, and glucagon receptors to increase energy expenditure and hepatic fat oxidation. This triple mechanism creates a synergistic metabolic effect.
Quick Reference — Retatrutide
10 / 15 / 20 / 30 mg vials
1 mL bacteriostatic water per vial
10–15 mg/mL (varies by vial)
Start: 0.5–1 mg/week. Titrate: +0.5–1 mg every 4 weeks. Target: 4–8 mg/week
Once weekly SC injection
SC injection (abdomen, thigh, upper arm)
Refrigerate; use within 28 days reconstituted
Requires bacteriostatic water for reconstitution — available in our store. TITRATE SLOWLY. Nausea, vomiting, and constipation common if escalated too fast. Rotate injection sites. Significant muscle loss risk — pair with high protein intake (2+ g/kg) and resistance training. Most potent weight loss peptide available.
For research purposes only. Not for human consumption. Always consult qualified professionals.
Pairs well with
Retatrutide + MOTS-C creates an elite metabolic stack — Retatrutide handles appetite and fat burning while MOTS-C optimises mitochondrial energy. Tesamorelin targets visceral fat specifically, and NAD+ supports cellular energy during caloric deficit.
Questions about Retatrutide?
Our team responds within 24 hours. Reach out for bulk pricing, stacking advice, or technical questions.